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                                        조화와 균형, 피부건강을 위한<br/>
                                        <span class="point0">스킨 마이크로바이옴 코스메슈틱스</span>
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                                    스킨 마이크로바이옴 밸런스의 유지를 통해,<br class="hidden show-sm"/>
                                    피부의 자연 방어력 및 자생력을 개선시킨 피부건강을 위한 코스메슈틱스
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                                        01
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                                        식물 유래 GRAS 미생물
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                                                    장내 미생물로서 GRAS (generally regarded as safe) 미생물이면서 또한 인체에 유익한 기능을 수행할 수 있는 프로바이오틱스 유산균을,
                                                    식물로 만든 국내 전통 슈퍼푸드-발효식품으로부터 분리하고 스크리닝 하였습니다.<br/>
                                                    면역기능 강화 (immunity enhancing) 및 장벽 강화 (intestinal epithelial strengthening)와 관련된 지표의 변화를 확인하고,<br class="hidden show-md"/>
                                                    항균 및 항진균 활성을 테스트한 후 가장 우수한 특성을 보이는 유산균을 선별하였습니다
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                                        02
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                                        스킨 마이크로바이옴 다양성 및 항상성 유지에 기여
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                                                    장내 미생물과 피부 미생물이 생성하고 배출하는 MVs (membrane vesicles)가<br class="hidden show-sm"/>
                                                    장내 및 피부 상의 미생물 생태계인 마이크로바이옴의 다양성을 훼손하지 않고 항상성을 유지하면서,<br class="hidden show-sm"/>
                                                    항균활성을 통해 유해성이 보다 더 큰 미생물들의 과도한 증식을 억제할 뿐만 아니라,<br class="hidden show-sm"/>
                                                    피부장벽 구성 단백질의 발현 증가 및 체내 면역기능 증강을 통해,<br class="hidden show-sm"/>
                                                    건강에 이로운 기능을 수행하는 것에 주목하였습니다.
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                                                            앰블링에 포함된 프로바이오틱스 유산균 MVs 농축 성분의 선택적인 박테리아 생육억제 효과
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                                                            앰블링에 포함된 프로바이오틱스 유산균 MVs 농축 성분의 광범위한 항균력
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                                                        <img src="[RESOURCE::img/sub_02_contents_img_005.png]" alt="Bacteria growth inhibition effect">
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                                        03
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                                        천연 방부시스템의 구현
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                                                    사용이 금지된 파라벤 (parabens)은 물론, 1-2 헥산디올 (1,2-hexanediol), 소르빈산칼륨 (potassium sorbate),<br class="hidden show-md"/>
                                                    벤조산나트륨 (Sodium benzoate) 또는 페녹시에탄올 등의 화장품에 사용되는 화학 보존제를 사용하지 않았습니다.<br class="hidden show-sm"/>
                                                    그럼에도 불구하고, 앰블링 코스메슈틱스는 기존 화장품과 같은 수준의 기간동안 보관 및 사용될 수 있습니다.
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                                        04
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                                        피부장벽 구성 단백질 발현 증대
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                                                    피부 아래에 존재하는 피부장벽층은 이를 구성하는 세포와 세포 사이의 좁은 간격을 유지하여 유해물질이 피부를 통해
                                                    체내로 유입되는 것을 방지하는 역할을 수행하는 “밀착연접” (Tight Junction, TJ) 구조를 포함하며,
                                                    몇몇 단백질들이 이러한 “밀착연접”의 구조를 유지하기 위해 필수적으로 요구됩니다.
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                                                            앰블링에 포함된 프로바이오틱스 유산균 MVs 농축 성분의 “밀착연접” 구조를 구성하는 단백질 발현증가
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                                        05
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                                        보습 및 피부자극에 대한 임상 효과
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                                                    앰블링에 포함된 프로바이오틱스 유산균 MVs 농축 성분은 임상 실험결과 우수한 보습효과를 나타냈음.<br/>
                                                    (서원대글로벌피부임상센터)
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                                                                수분 지속력 변화 (AU)
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                                                                수분 지속력 개선율 (%)
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                                                                <img src="[RESOURCE::img/sub_02_contents_img_009.png]" alt="수분 지속력 개선율 (%)">
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